Research interests
We aim to characterize changes in regions that may serve as potential biomarkers for diagnosis of AD and prognosis of MCI conversion using multi-modal We hope to provide insight into the microstructural change in aging and neurodegenerative diseases. Neural substrates of language processing in proficient bilinguals using fMRI 以核振造影探索雙語人士語言處理 We are interested in how language learning shapes cognition and how figurativeness and analogical reasoning interact in the bilingual brain. This may provide valuable implications for research on higher-order cognition, and language teaching and acquisition. Semantic memory in traumatic brain injury (TBI) patients. 腦傷病患之語意記憶 This project is in collaboration with Dr. Pratik Mukherjee and Dr. Tracy Luks at University of California, San Francisco, USA. The project aims to explore semantic competition in traumatic brain injury (TBI) patients. Visuospatial attention in TBI 腦傷病患之視覺空間注意力的探討 This project is in collaboration with Dr. Pratik Mukherjee and Dr. Tracy Luks at University of California, San Francisco, USA. We aim to investigate the attention network in TBI patients and healthy controls. Functional connectivity in TBI and stroke using MEG 以 腦磁波儀研究腦傷以及中風病患之腦功能連結度 This project is in collaboration with Dr. Srikantan S. Nagarajan, the derector of MEG lab at UCSF. We would like to study the brain oscillations and electrophysiology at the resting state as well as correlations of functional connectivity with neuropsychological performance. Multivariate analysis and dynamical causal modeling of fMRI data 以多變量分析及動態因果模型探討正常人與病人的腦功能連結度 We use multivariate analyses to characterize functional activations in healthy and patient populations. The patient populations include patients with schizophrenia, aging, Alzheimer's disease and TBI. We also perform various types of modeling of imaging data.
Projects PI: National Health Research Institutes (NHRI) 國衛院計畫 2013/1/1-2016/12/31 Approaches to White Matter Changes in Aging, Mild Cognitive Impairment and Alzheimer's Disease 老化，輕度認知障礙、阿茲海默症與白質變化的關係
National Science Council(NSC) 國科會計畫 2013/8/1-2014/7/31 The Neural Bases for Verbal Reasoning 語文推理之神經基礎 2012/8/1-2013/7/31 An fMRI Study of Figurative Language Processing in Bilingual Students 以磁振照影探索大學生對譬喻句之理解 2011/8/1-2012/10/31 The Neural Bases for Semantic Memory and Ambiguity 語意記憶及語意歧異之神經基礎 Non-NSC Grant 2012/1/1-2013/12/31 The Culture- and Mind-Basis for Learning Process Sub-project: The Neural and Mind Bases for Dialectic Reasoning: Exploration of Brain Functions 辯證思維的心智基礎：腦功能的探索 清華大學與台大醫院新竹分院合作研究計畫 2013/1/1-2013/12/31 Diffusion Imaging of White Matter Change in Patients with Stroke after Melodic Intonation Therapy 擴散磁振造影研究韻律語調療法後中風病患之大腦白質變化 長清計畫 2012/1/1-2012/12/31 Multimodal Imaging Approaches to Brain Damages and Motor Imagery in Children with Celebral Palsy 以多模式醫學影響觀察腦性麻痺兒童之腦損及動作意象 Teaching Development Grant (課程與教學創新計畫) 2011/1/1-2013/6/28 Language and Cognition 語言與認知 2012/9/17-2012/12/31 Language and Brain 語言與大腦 Co-PI: National Science Council(NSC) 2013/1/1-2013/12/31 Functional Changes in the Brain Caused by Pregnancy Induced Hypertension 以核磁共振攝影來評估妊娠高血壓疾病對孕婦腦部結構與功能之變化
2012/3/1-2015/2/28 Diagnosis of the Parkinson's Disease using Diffusion Tensor Imaging 擴散磁振造影在帕金森氏症之診斷
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